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Invitrogen
Human TMEM123 (aa 36-93) Control Fragment Recombinant Protein
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产品信息
RP-108478
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
ANIENSGLPHNSSANSTETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTA
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (34%), Rat (34%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111556. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Transmembrane protein 123, or Tmem123, is a single-pass type I membrane protein and belongs to the CD164 family. Tmem123 acts as a novel marker for DC maturation. DCs are also known as professional antigen-presenting cells. It is reported that the Tmem123 molecule may be closely associated with the cell surface expression of CD40. It was also reported previously that Tmem123 protein may also be responsible for oncotic cell death, which is characterized by cell swelling, organelle swelling, vacuolization, increased membrane permeability and cell adhesion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KCT-3; keratinocytes associated transmembrane protein 3; Keratinocytes-associated transmembrane protein 3; Porimin; pro oncosis receptor inducing membrane injury; Pro-oncosis receptor inducing membrane injury; serine/threonine-rich receptor; Transmembrane protein 123
基因别名: KCT3; PORIMIN; PORMIN; PSEC0111; TMEM123; UNQ641/PRO1271
UniProt ID: (Human) Q8N131
Entrez Gene ID: (Human) 114908
