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Invitrogen
Human ZNF140 (aa 67-148) Control Fragment Recombinant Protein
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产品信息
RP-100882
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
GKREVKRDLFSVSESSGEIKDFSPKNVIYDDSSQYLIMERILSQGPVYSSFKGGWKCKDHTEMLQENQGCIRKVTVSHQEAL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (28%), Rat (28%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61714. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The ZNF140 gene encodes a zinc finger protein that contains KRAB (Kruppel-associated box) domains, which are known to function as transcriptional repressors. These domains are located at the N-terminus of the protein and are involved in mediating protein-protein interactions, critical for gene silencing. ZNF140 is part of a large family of zinc finger proteins, which play significant roles in regulating gene expression by binding to specific DNA sequences. The KRAB domains of ZNF140 enable it to interact with other transcriptional repressors and recruit corepressor complexes, leading to chromatin remodeling and transcriptional repression.
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生物信息学
蛋白别名: Zinc finger protein 140
基因别名: pHZ-39; ZNF140
UniProt ID: (Human) P52738
Entrez Gene ID: (Human) 7699
