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Gibco
Mouse IL-2 Recombinant Protein
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产品信息
PMC0023
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
Amount
1 mg
保存条件
4°C
运输条件
Wet ice
产品详细信息
Carrier-Free
Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Lyophilized mouse IL-2 should be reconstituted in 100 mM acetic acid to a concentration of 0.1-1.0 mg/mL to regain full activity. Stock solutions should be apportioned into working aliquots and stored at ≤-20°C. Further dilutions should be made in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.
Storage: Lyophilized mouse IL-2 should be stored at 2°C to 8°C, preferably desiccated. Store reconstituted mouse IL-2 at ≤-20°C (not in a frost-free freezer). Keep freeze-thaw cycles to a minimum.
靶标信息
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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