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Invitrogen
Rat Ghrelin (aa 252-267) Synthetic Peptide
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产品信息
PEP-290
产品规格
分类
Synthetic
类型
Peptide
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PEP-290 is a 23 amino acid synthetic peptide whose sequence is derived from the rat Obestatin. The sequence of this peptide is (amino to carboxy terminus): F-N-A-P-F-D-V-G-I-K-L-S-G-A-Q-Y-Q-Q-H-G-R-A-L
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, Obestatin, catalog # PA1-1070. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
靶标信息
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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