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Invitrogen
Rat Perilipin A/B (aa 1-17) Synthetic Peptide
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产品信息
PEP-170
产品规格
分类
Synthetic
类型
Peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PEP-170 is an 18 amino acid synthetic peptide whose sequence is derived from rat perilipin A and B protein. The sequence of this peptide is (amino to carboxy terminus): M (1)-S-M-N-K-G-P-T-L-L-D-G-D-L-P-E-Q (17)-C
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat perilipin A and B, catalog # PA1-1052. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
靶标信息
Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species. Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin. Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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