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Invitrogen
Rat alpha COP (aa 1-19) Synthetic Peptide
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产品信息
PEP-125
产品规格
分类
Synthetic
类型
Peptide
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PEP-125 is a 19 amino acid synthetic peptide whose sequences are derived from rat COPI alpha protein. The sequence of this peptide is (amino to carboxy terminus): M (1)-L-T-K-F-E-T- K-S-A-R-V-K-G-L-S-F-H-P (19)-C
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat COPI alpha, catalog # PA1-067. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
靶标信息
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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