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Abnova
A1CF Polyclonal Antibody, MaxPab™
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产品信息
H00029974-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A1CF (NP_620311.1, 1 a.a. approximately 594 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEAVCLGTCP EPEASMSTAI PGLKKGNNAL QSIILQTLLE KENGQRKYGG PPPGWDAAPP ERGCEIFIGK LPRDLFEDEL IPLCEKIGKI YEMRMMMDFN GNNRGYAFVT FSNKVEAKNA IKQLNNYEIR NGRLLGVCAS VDNCRLFVGG IPKTKKREEI LSEMKKVTEG VVDVIVYPSA ADKTKNRGFA FVEYESHRAA AMARRKLLPG RIQLWGHGIA VDWAEPEVEV DEDTMSSVKI LYVRNLMLST SEEMIEKEFN NIKPGAVERV KKIRDYAFVH FSNREDAVEA MKALNGKVLD GSPIEVTLAK PVDKDSYVRY TRGTGGRGTM LQGEYTYSLG QVYDPTTTYL GAPVFYAPQT YAAIPSLHFP ATKGHLSNRA IIRAPSVRGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF
靶标信息
Mammalian apolipoprotein B mRNA undergoes site-specific Cto U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and acomplementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNPR family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apo-B RNA editing protein; apobec-1 complementation factor (ACF) (ASP); APOBEC-1 stimulating protein; APOBEC1 complementation factor; APOBEC1-stimulating protein; MGC163391; RP11-564C4.2
基因别名: A1CF; ACF; ACF64; ACF65; APOBEC1CF; ASP
UniProt ID: (Human) Q9NQ94
Entrez Gene ID: (Human) 29974
