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产品信息
PA5-55379
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human AASDHPPT
偶联物
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2637517
产品详细信息
Immunogen sequence: EWAFEESKID EHHFVAVALR KPDGSRHQDV PSQDDSKPTQ RQFTILNFND LMSSAVPMTP EDPSFWDCFC FTEEIPIRNG TKS
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
靶标信息
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4'-phosphopantetheinyl transferase; AASD-PPT; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; DKFZp566E2346; holo ACP synthase; holo-[acyl-carrier-protein] synthase; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; LYS5 ortholog
基因别名: 2010309J24Rik; 2810407B07Rik; AASD-PPT; AASDHPPT; ACPS; CGI-80; HAH-P; HSPC223; LYS2; LYS5; x0005
UniProt ID: (Human) Q9NRN7, (Mouse) Q9CQF6
Entrez Gene ID: (Human) 60496, (Mouse) 67618
分子生物学功能:
transferase
magnesium ion binding
protein binding
holo-[acyl-carrier-protein] synthase activity
cardiolipin synthase activity
transferase activity
UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity
GDP-mannose:serine-protein mannose-1-phosphotransferase activity
archaetidylserine synthase activity
metal ion binding
