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Invitrogen
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Immunogen sequence: AEWLGLLGDE QVPQAESILD ALSKHLVMKL SYGPEEKDMI VMRDSFGIRH PSGHLEHKTI DLVAYGDING FSAMAKTVGL PTAMAAKMLL DGEIGAKGLM GPFSKEIYGP ILERIKA
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha-aminoadipate semialdehyde synthase; Alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipic semialdehyde synthase; LKR/SDH; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase
基因别名: AASS; LKR/SDH; LKRSDH; LORSDH
UniProt ID: (Human) Q9UDR5
Entrez Gene ID: (Human) 10157