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Invitrogen
ABCB8 Polyclonal Antibody
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产品信息
PA5-120826
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Protein (or fragment)
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: MCF7, Jurkat, HepG2, HeLa, Mouse heart, Mouse skin, Mouse kidney, Rat heart. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein.
Immunogen sequence: GFEVLKDFTL TLPPGKIVAL VGQSGGGKTT VASLLERFYD PTAGVVMLDG RDLRTLDPSW LRGQVVGFIS QEPVLFGTTI MENIRFGKLE ASDEEVYTAA REANAHEFIT SFPEGYNTVV GERGTTLSGG QKQRLAIARA LIKQPTVLIL DEATSALDAE SERVVQEALD RASAGRTVLV IAHRLSTVRG AHCIVVMADG RVWEAGTHEE LLKKGGLYAE LIRRQALDAP RTAAPPPKKP EGPRSHQHKS
靶标信息
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ABC transporter 8; ABCB8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 8; ATP-binding cassette, sub-family B, member 8; M-ABC1; mitochondrial ABC protein; Mitochondrial ATP-binding cassette 1; Mitochondrial potassium channel ATP-binding subunit; Mitochondrial sulfonylurea-receptor; MITOSUR
基因别名: 4833412N02Rik; AA409895; ABCB8; EST328128; M-ABC1; MABC1; MITOSUR
UniProt ID: (Human) Q53GM0, (Mouse) Q9CXJ4, (Rat) Q5RKI8
Entrez Gene ID: (Human) 11194, (Mouse) 74610, (Rat) 362302
