应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1-5 µg/mL | - |
免疫细胞化学 (ICC/IF) |
10 µg/mL | - |
酶联免疫吸附实验 (ELISA) |
Assay-Dependent | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2b, kappa |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
4F4 |
抗原 |
ABCB9 (NP_062571, 482 a.a. ~ 580 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.0 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4 |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2577125 |
Peptide Sequence: FIDRQPTMVH DGSLAPDHLE GRVDFENVTF TYRTRPHTQV LQNVSFSLSP GKVTALVGPS GSGKSSCVNI LENFYPLEGG RVLLDGKPIS AYDHKYLHR
The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3' of the DNA lesion while the ERCC1 / XPF complex makes the 5' incision. ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ABC transporter 9 protein; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; TAP-like protein; TAPL
基因别名: ABCB9; EST122234; KIAA1520; TAPL
UniProt ID: (Human) Q5W9G7
Entrez Gene ID: (Human) 23457