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NeoBiotechnologies
ABCC4/ATP Binding Cassette Subfamily C Member 4 (Drug Target) Monoclonal Antibody (ABCC4/9018)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
10257-MSM2-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
ABCC4/9018
抗原
Recombinant fragment (around aa1-200) of human ABCC4 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control: but is barely detectable in liver. Widely expressed with particularly high levels in prostate
Cellular Location: Membrane.
靶标信息
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); EST170205; MRP/cMOAT-related ABC transporter; multi-specific organic anion transporter B; multidrug resistance-associated protein 4; RP11-74A12.1; transporter; alternatively spliced; truncated; MRP/cMOAT-related ABC transporter; unnamed protein product
基因别名: MOAT-B; MOATB; MRP4
UniProt ID: (Human) O15439
Entrez Gene ID: (Human) 10257
guanine nucleotide transmembrane transporter activity
protein binding
ATP binding
xenobiotic-transporting ATPase activity
prostaglandin transmembrane transporter activity
urate transmembrane transporter activity
purine nucleotide transmembrane transporter activity
glutathione S-conjugate-exporting ATPase activity
bile acid-exporting ATPase activity
efflux transmembrane transporter activity
15-hydroxyprostaglandin dehydrogenase (NAD+) activity
ATPase activity
transmembrane transporter activity
glutathione transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of substances
xenobiotic transporter activity
ABC-type transporter activity
3',5'-cyclic GMP transmembrane-transporting ATPase activity
platelet degranulation
xenobiotic metabolic process
drug transmembrane transport
bile acid and bile salt transport
prostaglandin transport
urate transport
prostaglandin secretion
glutathione transmembrane transport
transmembrane transport
cilium morphogenesis
cAMP transport
leukotriene transport
export across plasma membrane
transport across blood-brain barrier
guanine nucleotide transmembrane transport
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