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Invitrogen
ABO Monoclonal Antibody (K21)
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产品信息
MA1-26518
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
K21
抗原
Tera-1 Teratocarcinoma cell line.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
4°C
运输条件
Wet ice
产品详细信息
MA1-26518 detects Blood Group Antigen Precursor from human samples.
MA1-26518 has been successfully used in immunohistochemistry (paraffin and frozen) procedures.
The MA1-26518 immunogen is Tera-1 Teratocarcinoma cell line.
靶标信息
Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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