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Proteintech
ACKR2 Monoclonal Antibody (1A3A2)
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产品信息
60046-1-IG
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A3A2
抗原
ACKR2 Fusion Protein Ag1941 (74-384 aa encoded by BC008816)
偶联物
形式
Liquid
浓度
0.83 mg/mL
纯化类型
Caprylic acid precipitation
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.1% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: YVPRRRMVE IYLLNLAISN LLFLVTLPFW GISVAWHWVF GSFLCKMVST LYTINFYSGI FFISCMSLDK YLEIVHAQPY HRLRTRAKSL LLATIVWAVS LAVSIPDMVF VQTHENPKGV WNCHADFGGH GTIWKLFLRF QQNLLGFLLP LLAMIFFYSR IGCVLVRLRP AGQGRALKIA AALVVAFFVL WFPYNLTLFL HTLLDLQVFG NCEVSQHLDY ALQVTESIAF LHCCFSPILY AFSSHRFRQY LKAFLAAVLG WHLAPGTAQA SLSSCSESSI LTAQEEMTGM NDLGERQSEN YPNKEDVGNK SA (74-384 aa encoded by BC008816)
靶标信息
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Atypical chemokine receptor 2; C-C chemokine receptor D6; CC-chemokine-binding receptor JAB61; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine binding protein 2; Chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; Chemokine-binding protein 2; Chemokine-binding protein D6
基因别名: ACKR2; CCBP2; CCR10; CCR9; CMKBR9; D6; hD6
UniProt ID: (Human) O00590
Entrez Gene ID: (Human) 1238
