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Invitrogen
ACOT9 Polyclonal Antibody
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ACOT9 Antibody (PA5-75868) in IHC (P)
Immunohistochemistry analysis of ACOT9 in paraffin-embedded human colon carcinoma tissue (cytoplasmic staining) and negative control (right, with PBS only). Samples were incubated with ACOT9 polyclonal antibody (Product # PA5-75868) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
产品信息
PA5-75868
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human ACOT9.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT9 (acyl-CoA thioesterase 9), also known as ACATE2, MT-ACT48 (mitochondrial acyl-CoA thioesterase of 48 kDa) or CGI-16, is a 406 amino acid member of the acyl-CoA hydrolase protein family. ACOT9 contains a C-terminal 80-amino acid domain that is conserved from mouse to human, suggesting that the C-terminus may confer the catalytic activity of ACOT9. The gene encoding ACOT9 is located on chromosome X and the expressed ACOT9 protein is localized to the mitochondrion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acyl coenzyme A thioester hydrolase 2; Acyl-CoA thioester hydrolase 9; Acyl-CoA thioesterase 9; acyl-Coenzyme A thioesterase 2, mitochondrial; Acyl-coenzyme A thioesterase 9, mitochondrial; Mitochondrial 48 kDa acyl-CoA thioester hydrolase 1; mitochondrial Acyl-CoA Thioesterase; Mt-ACT48.1; MTE-2; p48; Protein U8
基因别名: 0610041P13Rik; ACATE2; ACOT9; C76421; CGI-16; MT-ACT48; MTACT48; p48; U8
UniProt ID: (Human) Q9Y305, (Mouse) Q9R0X4
Entrez Gene ID: (Human) 23597, (Mouse) 56360, (Rat) 302640
acetyl-CoA hydrolase activity
acyl-CoA hydrolase activity
carboxylic ester hydrolase activity
protein binding
CoA hydrolase activity
palmitoyl-CoA hydrolase activity
hydrolase activity
2-oxoglutaryl-CoA thioesterase activity
2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity
3-isopropylbut-3-enoyl-CoA thioesterase activity
glutaryl-CoA hydrolase activity
esterase
