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Proteintech
ACP5 Polyclonal Antibody
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产品信息
11594-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ACP5 Fusion Protein Ag2065 (1-325 aa encoded by BC025414)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDMWTALLI LQALLLPSLA DGATPALRFV AVGDWGGVPN APFHTAREMA NAKEIARTVQ ILGADFILSL GDNFYFTGVQ DINDKRFQET FEDVFSDRSL RKVPWYVLAG NHDHLGNVSA QIAYSKISKR WNFPSPFYRL HFKIPQTNVS VAIFMLDTVT LCGNSDDFLS QQPERPRDVK LARTQLSWLK KQLAAAREDY VLVAGHYPVW SIAEHGPTHC LVKQLRPLLA TYGVTAYLCG HDHNLQYLQD ENGVGYVLSG AGNFMDPSKR HQRKVPNGYL RFHYGTEDSL GGFAYVEISS KEMTVTYIEA SGKSLFKTRL PRRARP (1-325 aa encoded by B C025414)
靶标信息
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: human purple acid phosphatase; Tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; Tartrate-resistant acid phosphatase type 5; TR-AP; TRAPase; TrATPase; Type 5 acid phosphatase
基因别名: ACP5; HPAP; TRACP5a; TRACP5b; TRAP; TrATPase
UniProt ID: (Human) P13686
Entrez Gene ID: (Human) 54
ossification
riboflavin metabolic process
negative regulation of cell adhesion
response to zinc ion
dephosphorylation
osteoclast differentiation
positive regulation of cell migration
response to lipopolysaccharide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of tumor necrosis factor production
negative regulation of superoxide anion generation
multicellular organismal response to stress
response to L-ascorbic acid
response to cytokine
negative regulation of nitric oxide biosynthetic process
bone resorption
negative regulation of inflammatory response
defense response to Gram-positive bacterium
bone morphogenesis
response to cholesterol
