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Purity is > 95% by SDS-PAGE.
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acyl-CoA synthetase 4; Arachidonate--CoA ligase; fatty acid-Coenzyme A ligase, long chain 4; fatty-acid-Coenzyme A ligase, long-chain 4; L MRX63; LACS 4; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; Long-chain-fatty-acid--CoA ligase 4; mACS4
基因别名: 9430020A05Rik; ACS4; ACSL4; AU018108; FACL4; LACS4; MRX63; MRX68
UniProt ID: (Human) O60488, (Mouse) Q9QUJ7
Entrez Gene ID: (Human) 2182, (Mouse) 50790