Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
ADAM8 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
23778-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ADAM8 Fusion Protein Ag17262 (145-494 aa encoded by BC115404)
偶联物
形式
Liquid
浓度
0.42 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is specific to ADAM8.
Immunogen sequence: EGGEGGRHA VYQAEHLLQT AGTCGVSDDS LGSLLGPRTA AVFRPRPGDS LPSRETRYVE LYVVVDNAEF QMLGSEAAVR HRVLEVVNHV DKLYQKLNFR VVLVGLEIWN SQDRFHVSPD PSVTLENLLT WQARQRTRRH LHDNVQLITG VDFTGTTVGF ARVSAMCSHS SGAVNQDHSK NPVGVACTMA HEMGHNLGMD HDENVQGCRC QERFEAGRCI MAGSIGSSFP RMFSDCSQAY LESFLERPQS VCLANAPDLS HLVGGPVCGN LFVERGEQCD CGPPEDCRNR CCNSTTCQLA EGAQCAHGTC CQECKVKPAG ELCRPKKDMC DLEEFCDGRH PECPEDAFQE N (145-494 aa encoded by BC115404)
靶标信息
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 8; ADAM; ADAM 8; ADAMs; CD156a; Cell surface antigen MS2; Disintegrin and metalloproteinase domain-containing protein 8; human leukocyte differentiation antigen; Macrophage cysteine-rich glycoprotein; metalloendopeptidases; MGC134985
基因别名: ADAM 8; ADAM8; CD156; CD156a; E430039A18Rik; MS2
UniProt ID: (Human) P78325, (Mouse) Q05910
Entrez Gene ID: (Human) 101, (Mouse) 11501
cell morphogenesis
angiogenesis
leukocyte migration involved in inflammatory response
positive regulation of acute inflammatory response
proteolysis
inflammatory response
positive regulation of protein processing
single organismal cell-cell adhesion
regulation of cell-cell adhesion
extracellular matrix disassembly
positive regulation of T cell differentiation in thymus
activation of MAPK activity involved in innate immune response
negative regulation of neuron apoptotic process
positive regulation of bone resorption
positive regulation of cell adhesion
lymphocyte chemotaxis
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
positive regulation of thymocyte apoptotic process
cellular response to hypoxia
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
positive regulation of neutrophil extravasation
positive regulation of fibronectin-dependent thymocyte migration
positive regulation of eosinophil migration
