Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1 µg/mL | - |
免疫沉淀 (IP) |
25 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2B |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
143303 |
抗原 |
Mouse myeloma cell line NS0-derived recombinant human ADAM8 ectodomain Asp158-Ser653 |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
0.5 mg/mL |
纯化类型 |
Protein A/G |
保存液 |
PBS with 5% trehalose |
内含物 |
No Preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2608284 |
In Western blots, less than 5% cross-reactivity with the ectodomains of recombinant human ADAM9, 10, 15, 17, and 19 is observed. This antibody detects an epitope within aa 201-497 of recombinant human ADAM8 which corresponds to the metalloprotease and disintegrin-like domains.
Reconstitute at 0.5 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 8; ADAM; ADAM 8; ADAMs; CD156a; Cell surface antigen MS2; Disintegrin and metalloproteinase domain-containing protein 8; human leukocyte differentiation antigen; metalloendopeptidases; MGC134985
基因别名: ADAM8; CD156; CD156a; MS2
UniProt ID: (Human) P78325
Entrez Gene ID: (Human) 101
分子生物学功能:
metalloprotease
