Proteintech

ADPGK Monoclonal Antibody (2B4B8)

Name: ADPGK Monoclonal Antibody (2B4B8)
Brand: Proteintech
SKU: 68034-1-IG150UL

查看其他10个ADPGK抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)

图: 1 / 6

ADPGK Antibody (68034-1-IG150UL) in WB

Various lysates (A549, LNCaP, HeLa, Jurkat, K-562, THP-1) were subjected to SDS PAGE followed by western blot with (Product # 68034-1-IG150UL) (ADPGK antibody) at dilution of 1:5,000 incubated at room temperature for 1.5 hours.

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Immunogen image

Immunogen Image ADPGK Monoclonal Antibody (2B4B8)

产品信息

68034-1-IG150UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

2B4B8

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

靶标信息

The ADPGK gene encodes ADP-dependent glucokinase, an enzyme distinct from the ATP-dependent hexokinases as it employs adenosine diphosphate (ADP) rather than ATP to phosphorylate glucose to glucose-6-phosphate. This gene, initially identified in archaeal species, has been co-opted into mammalian systems where it plays roles primarily in glycolytic processes. Structurally, the mammalian ADPGK differs from its archaeal counterpart, exemplified by the rearrangement of its secondary structures, such as the alpha2 and alpha3 helices. These helices are replaced by an extended beta-strand region, indicating evolutionary adaptations for function in higher organisms like mice. Although its precise physiological role remains partially defined, ADPGK is notably expressed in both hematopoietic lineages and tumor tissues, suggesting potential significance in cancer biology and energy metabolism.

仅用于科研。不用于诊断过程。未经明确授权不得转售。