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Immunogen sequence: NRPIPHIDPS RPMTPQQRRL QQRRLQHRLR LRAQMRLRRL NATTTLGPHT VPPTLPPAPA TTLSTTIEPW GLIPPTTAGW EESETETYTE VVTEFGTEVE PEFGTKVEPE FETQLEPEFE TQLEPEFEEE EEEEKEEEIA TGQAFPFTTV ETYTVNFGDF
The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adipocyte enhancer-binding protein 1; AE-binding protein 1; Aortic carboxypeptidase-like protein; FLJ33612
基因别名: ACLP; AEBP1
UniProt ID: (Human) Q8IUX7, (Rat) A2RUV9, (Mouse) Q640N1
Entrez Gene ID: (Human) 165, (Rat) 305494, (Mouse) 11568
分子生物学功能: protease