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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 233-422 of human AGK. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.95 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2809118 |
Immunogen sequence: KAAHFFSTLK EWPQTHQASI SYTGPTERPP NEPEETPVQR PSLYRRILRR LASYWAQPQD ALSQEVSPEV WKDVQLSTIE LSITTRNNQL DPTSKEDFLN ICIEPDTISK GDFITIGSRK VRNPKLHVEG TECLQASQCT LLIPEGAGGS FSIDSEEYEA MPVEVKLLPR KLQFFCDPRK REQMLTSPTQ; Positive Samples: 293T, SH-SY5Y, HepG2, HeLa, 22Rv1, BT-474, K-562, Rat brain; Cellular Location: Mitochondrion membrane
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acylglycerol kinase, mitochondrial; FLJ10842; hAGK; HsMuLK; multi-substrate lipid kinase; Multiple substrate lipid kinase
基因别名: AGK; CATC5; CTRCT38; MTDPS10; MULK; RGD1562046
UniProt ID: (Human) Q53H12
Entrez Gene ID: (Human) 55750, (Rat) 502749
分子生物学功能:
kinase
