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A suggested positive control is mouse liver tissue lysate.
PA5-20813 can be used with blocking peptide PEP-0927.
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Angiotensin ii at2; angiotensin II receptor, type 2; angiotensin II type 2 receptor; Angiotensin II type-2 receptor; angiotensin receptor 2; AT2; AT2 receptor; Type-2 angiotensin II receptor
基因别名: AGTR2; AI316812; AT2; AT2-R; AT2R; AT2R; ATGR2; AW107640; MRX88
UniProt ID: (Human) P50052, (Rat) P35351, (Mouse) P35374
Entrez Gene ID: (Human) 186, (Rat) 24182, (Mouse) 11609