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Proteintech
AIFM2 Polyclonal Antibody
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产品信息
20886-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AIFM2 Fusion Protein Ag13412 (1-373 aa encoded by BC023601)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGSQVSVES GALHVVIVGG GFGGIAAASQ LQALNVPFML VDMKDSFHHN VAALRASVET GFAKKTFISY SVTFKDNFRQ GLVVGIDLKN QMVLLQGGEA LPFSHLILAT GSTGPFPGKF NEVSSQQAAI QAYEDMVRQV QRSRFIVVVG GGSAGVEMAA EIKTEYPEKE VTLIHSQVAL ADKELLPSVR QEVKEILLRK GVQLLLSERV SNLEELPLNE YREYIKVQTD KGTEVATNLV ILCTGIKINS SAYRKAFESR LASSGALRVN EHLQVEGHSN VYAIGDCADV RTPKMAYLAG LHANIAVANI VNSVKQRPLQ AYKPGALTFL LSMGRNDGVG QISGFYVGRL MVRLTKSRDL FVSTSWKTMR QSPP (1-373 aa encoded by BC023601)
靶标信息
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AMID; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; Ferroptosis suppressor protein 1; FSP1; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; RP11-367H5.2
基因别名: 5430437E11Rik; AIFM2; AMID; D730001I10Rik; PRG3
UniProt ID: (Human) Q9BRQ8, (Mouse) Q8BUE4
Entrez Gene ID: (Human) 84883, (Mouse) 71361
DNA binding
electron-transferring-flavoprotein dehydrogenase activity
flavin adenine dinucleotide binding
NADH dehydrogenase (ubiquinone) activity
N-ethylmaleimide reductase activity
oxidoreductase activity
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
epoxyqueuosine reductase activity
oxidoreductase
metabolite interconversion enzyme
