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Proteintech
AKAP12 Polyclonal Antibody
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产品信息
25199-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AKAP12 Fusion Protein Ag17769 (1433-1782 aa encoded by BC157067)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ETANILETG ETLEPAGAHL VLEEKSSEKN EDFAAHPGED AVPTGPDCQA KSTPVIVSAT TKKGLSSDLE GEKTTSLKWK SDEVDEQVAC QEVKVSVAIE DLEPENGILE LETKSSKLVQ NIIQTAVDQF VRTEETATEM LTSELQTQAH VIKADSQDAG QETEKEGEEP QASAQDETPI TSAKEESEST AVGQAHSDIS KDMSEASEKT MTVEVEGSTV NDQQLEEVVL PSEEEGGGAG TKSVPEDDGH ALLAERIEKS LVEPKEDEKG DDVDDPENQN SALADTDASG GLTKESPDTN GPKQKEKEDA QEVELQEGKV HSESDKAITP QAQEELQKQE RESAKSELTE S (1433-1782 aa encoded by BC157067)
靶标信息
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; A-kinase anchor protein 12; A-kinase anchor protein 250 kDa; A-kinase anchor protein, 250kDa; AKAP 250; AKAP-12; gercelin; Germ cell lineage protein gercelin; Gravin; kinase scaffold protein gravin; Myasthenia gravis autoantigen; myasthenia gravis autoantigen gravin; Src-Suppressed C Kinase Substrate; SSeCKS; SSeCKS, Gravin, AKAP250; testis specific gene A12; v-src suppressed transcript 5
基因别名: AI317366; AKAP12; AKAP12A; AKAP12B; AKAP12G; AKAP250; Gag12; Srcs5; SSeCKS; Tsga12
UniProt ID: (Human) Q02952, (Mouse) Q9WTQ5, (Rat) Q5QD51
Entrez Gene ID: (Human) 9590, (Mouse) 83397, (Rat) 83425
