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Invitrogen
AKR1B1 Monoclonal Antibody (K92029_13G7)
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AKR1B1 Antibody (MA5-55881) in IHC (P)
Immunohistochemistry analysis of AKR1B1 in paraffin-embedded adrenal gland tissue. Sample was incubated with AKR1B1 monoclonal antibody (Product # MA5-55881) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temper... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-55881
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
K92029_13G7
抗原
Recombinant human AKR1B1 (immunogen range is 11-290).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Sequence of this protein is as follows: AKMPILGLGT WKSPPGQVTE AVKVAIDVGY RHIDCAHVYQ NENEVGVAIQ EKLREQVVKR EELFIVSKLW CTYHEKGLVK GACQKTLSDL KLDYLDLYLI HWPTGFKPGK EFFPLDESGN VVPSDTNILD TWAAMEELVD EGLVKAIGIS NFNHLQVEMI LNKPGLKYKP AVNQIECHPY LTQEKLIQYC QSKGIVVTAY SPLGSPDRPW AKPEDPSLLE DPRIKAIAAK HNKTTAQVLI RFPMQRNLVV IPKSVTPERI AENFKVFDFE LSSQDMTTLL
靶标信息
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AKR1B1; aldehyde reductase 1; aldo-keto reductase family 1; aldose reductase; aldose reductase (EC 1.1.1.21); Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase); unnamed protein product
基因别名: ADR; ALDR1; ALR2; AR
UniProt ID: (Human) P15121
Entrez Gene ID: (Human) 231
retinal dehydrogenase activity
alditol:NADP+ 1-oxidoreductase activity
protein binding
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D-xylose:NADP reductase activity
L-arabinose:NADP reductase activity
prostaglandin H2 endoperoxidase reductase activity
glyceraldehyde oxidoreductase activity
allyl-alcohol dehydrogenase activity
aryl-alcohol dehydrogenase (NADP+) activity
L-glucuronate reductase activity
glycerol dehydrogenase (NADP+) activity
NADP-retinol dehydrogenase activity
retinoid metabolic process
carbohydrate metabolic process
sorbitol metabolic process
prostaglandin metabolic process
C21-steroid hormone biosynthetic process
retinol metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
fructose biosynthetic process
cellular hyperosmotic salinity response
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