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Invitrogen
AKR1B10 Polyclonal Antibody, DyLight™ 488
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产品信息
PA5-23020
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A highly specific 15 amino acid portion of human AKR1B10
偶联物
激发/发射光谱
492/519 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
保存条件
4°C, store in dark
运输条件
Wet ice
RRID
产品详细信息
This antibody does not cross react with mouse, rat or rabbit.
靶标信息
AKR1B10, a 316aa protein, catalyzes efficient reduction ofaliphatic and aromatic aldehydes. It the first cytosolic NADP (H)-dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications.It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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