Search
Invitrogen
AKR1C1/AKR1C2 Recombinant Rabbit Monoclonal Antibody (8B2)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
AKR1C1/AKR1C2 Antibody (MA573136) in WB
Western blot analysis of AKR1C1/AKR1C2 in Rat kidney lysates (25 µg/lane). Samples were incubated with AKR1C1/AKR1C2 Recombinant Monoclonal (Product # MA573136) at 1:1,000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA573136
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
8B2
抗原
KLH conjugated synthetic peptide derived from human AKR1C1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.26 mg/mL
规格
26 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 17-alpha-HSD; 17-alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-alpha-HSD; 20alpha-hydroxysteroid dehydrogenase; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-HSD3; 3-alpha-hydroxysteroid dehydrogenase; 3beta-hydroxysteroid 3-dehydrogenase; Aldo-keto reductase family 1 member C1; Aldo-keto reductase family 1 member C2; Aldo-keto reductase family 1 member C21; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C21; aldo-keto reductase family 1, member C6; Chlordecone reductase homolog HAKRC; Chlordecone reductase homolog HAKRD; DD-2; DD/BABP; DD1; Dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 2; Dihydrodiol dehydrogenase/bile acid-binding protein; HBAB; High-affinity hepatic bile acid-binding protein; type 5 17beta-hydroxysteroid dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase
基因别名: AKR1C1; AKR1C2; Akr1c21; Akr1c6; DDH; DDH1; DDH2; Hsd17b5
UniProt ID: (Rat) Q6AYQ2
Entrez Gene ID: (Rat) 307092, (Rat) 291283
retinal dehydrogenase activity
estradiol 17-beta-dehydrogenase activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
androsterone dehydrogenase activity
testosterone 17-beta-dehydrogenase (NADP+) activity
alditol:NADP+ 1-oxidoreductase activity
oxidoreductase activity
phenanthrene 9,10-monooxygenase activity
carboxylic acid binding
bile acid binding
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ketosteroid monooxygenase activity
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
oxidoreductase
reductase
metabolite interconversion enzyme
response to drug
response to estrogen
daunorubicin metabolic process
doxorubicin metabolic process
oxidation-reduction process
cellular response to jasmonic acid stimulus
prostaglandin metabolic process
G-protein coupled receptor signaling pathway
digestion
steroid metabolic process
positive regulation of cell proliferation
epithelial cell differentiation
progesterone metabolic process
positive regulation of protein kinase B signaling
cellular response to prostaglandin D stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
