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Proteintech
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Immunogen sequence: MNPFWSMST SSVRKRSEGE EKTLTGDVKT SPPRTAPKKQ LPSIPKNALP ITKPTSPAPA AQSTNGTHAS YGPFYLEYSL LAEFTLVVKQ KLPGVYVQPS YRSALMWFGV IFIRHGLYQD GVFKFTVYIP DNYPDGDCPR LVFDIPVFHP LVDPTSGELD VKRAFAKWRR NHNHIWQVLM YARRVFYKID TASPLNPEAA VLYEKDIQLF KSKVVDSVKV CTARLFDQPK IEDPYAISFS PWNPSVHDEA REKMLTQKKP EEQHNKSVHV AGLSWVKPGS VQPFSKEEKT VAT (1-292 aa encoded by BC001134)
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AKT-interacting protein; FT1; fused toes homolog; Fused toes protein; Fused toes protein homolog
基因别名: AKTIP; AL023020; Fif; Ft; FT1; FTS
UniProt ID: (Human) Q9H8T0, (Rat) Q5FVH4, (Mouse) Q64362
Entrez Gene ID: (Human) 64400, (Rat) 291906, (Mouse) 14339