Proteintech

ALDH3A1 Polyclonal Antibody, CoraLite® Plus 488

Name: ALDH3A1 Polyclonal Antibody, CoraLite\u00AE Plus 488
Brand: Proteintech
SKU: CL488-15578

查看其他21个ALDH3A1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

ALDH3A1 Antibody in Immunocytochemistry (ICC/IF)

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ALDH3A1 Antibody (CL488-15578) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using CoraLite® Plus 488 ALDH3A1 antibody (CL488-15578) at dilution of 1:200.

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产品信息

CL488-15578

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

1:50-1:500

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ALDH3A1 fusion protein Ag7977

偶联物

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

激发/发射光谱

493/522 nm

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

内含物

0.05% ProClin 300

保存条件

-20°C, store in dark

运输条件

Wet ice

产品详细信息

Immunogen sequence: LGVVLVIGT WNYPFNLTIQ PMVGAIAAGN AVVLKPSELS ENMASLLATI IPQYLDKDLY PVINGGVPET TELLKERFDH ILYTGSTGVG KIIMTAAAKH LTPVTLELGG KSPCYVDKNC DLDVACRRIA WGKFMNSGQT CVAPDYILCD PSIQNQIVEK LKKSLKEFYG EDAKKSRDYG RIISARHFQR VMGLIEGQKV AYGGTGDAAT RYIAPTILTD VDPQSPVMQE EIFGPVLPIV CVRSLEEAIQ FINQREKPLA LYMFSSNDKV IKKMIAETSS GGVAANDVIV HITLHSLPFG GVGNSGMGSY HGKKSFETFS HRRSCLVRPL MNDEGLKVRY PPSPAKMTQH

靶标信息

Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: alcohol dehydrogenase family 3, subfamily A1; Aldehyde dehydrogenase (Ahd-c); Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family, member A1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); aldehyde dehydrogenase 3A1; Aldehyde dehydrogenase 4; aldehyde dehydrogenase class 3; Aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase family 3 subfamily A1; aldehyde dehydrogenase family 3, member A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Dioxin-inducible aldehyde dehydrogenase 3; HTC-ALDH; MGC10406; stomach aldehyde dehydrogenase; Tumor-associated aldehyde dehydrogenase; tumor-associated aldehyde dehydrogenase tumor ALDH

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基因别名: Ahd-4; Ahd-c; Ahd4; AHDC; Aldd; Aldh; ALDH3; ALDH3A1; Aldh4; ALDHIII

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UniProt ID: (Human) P30838, (Mouse) P47739, (Rat) P11883

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Entrez Gene ID: (Human) 218, (Mouse) 11670, (Rat) 25375

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功能

3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity aldehyde dehydrogenase [NAD(P)+] activity protein binding alcohol dehydrogenase (NADP+) activity benzaldehyde dehydrogenase (NAD+) activity oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor dehydrogenase

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