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Proteintech
ALDH4A1 Polyclonal Antibody
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产品信息
11604-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ALDH4A1 Fusion Protein Ag2147 (246-563 aa encoded by BC023600)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: YRILREAGL PPNIIQFVPA DGPLFGDTVT SSEHLCGINF TGSVPTFKHL WKQVAQNLDR FHTFPRLAGE CGGKNFHFVH RSADVESVVS GTLRSAFEYG GQKCSACSRL YVPHSLWPQI KGRLLEEHSR IKVGDPAEDF GTFFSAVIDA KSFARIKKWL EHARSSPSLT ILAGGKCDDS VGYFVEPCIV ESKDPQEPIM KEEIFGPVLS VYVYPDDKYK ETLQLVDSTT SYGLTGAVFS QDKDVVQEAT KVLRNAAGNF YINDKSTGSI VGQQPFGGAR ASGTNDKPGG PHYILRWTSP QVIKETHKPL GDWSYAYMQ (246-563 aa encoded by BC023600)
靶标信息
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: aldehyde dehydrogenase 4 family, member A1; Aldehyde dehydrogenase family 4 member A1; Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; L-glutamate gamma-semialdehyde dehydrogenase; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; P5C dehydrogenase; RP11-128M10.1
基因别名: A930035F14Rik; Ahd-1; Ahd1; ALDH4; ALDH4A1; Aldh5a1; E330022C09; P5CD; P5CDH; P5cdhl; P5cdhs; Ssdh1
UniProt ID: (Human) P30038, (Mouse) Q8CHT0
Entrez Gene ID: (Human) 8659, (Rat) 641316, (Mouse) 212647
1-pyrroline-5-carboxylate dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
electron carrier activity
identical protein binding
structural molecule activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
oxidoreductase activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
