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Proteintech
ALDH6A1 Polyclonal Antibody
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产品信息
20452-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ALDH6A1 Fusion Protein Ag13879 (194-535 aa encoded by BC004909)
偶联物
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: WMFPMAMVC GNTFLMKPSE RVPGATMLLA KLLQDSGAPD GTLNIIHGQH EAVNFICDHP DIKAISFVGS NKAGEYIFER GSRHGKRVQA NMGAKNHGVV MPDANKENTL NQLVGAAFGA AGQRCMALST AVLVGEAKKW LPELVEHAKN LRVNAGDQPG ADLGPLITPQ AKERVCNLID SGTKEGASIL LDGRKIKVKG YENGNFVGPT IISNVKPNMT CYKEEIFGPV LVVLETETLD EAIQIVNNNP YGNGTAIFTT NGATARKYAH LVDVGQVGVN VPIPVPLPMF SFTGSRSSFR GDTNFYGKQG IQFYTQLKTI TSQWKEEDAT LSSPAVVMPT MGR (194-535 aa encoded by BC004909)
靶标信息
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: aldehyde dehydrogenase 6 family, member A1; Aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; malonate-semialdehyde dehydrogenase; Malonate-semialdehyde dehydrogenase [acylating]; methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSDH; testicular tissue protein Li 122
基因别名: 1110038I05Rik; AI314632; ALDH6A1; MMSADHA; MMSDH
UniProt ID: (Human) Q02252, (Rat) Q02253, (Mouse) Q9EQ20
Entrez Gene ID: (Human) 4329, (Rat) 81708, (Mouse) 104776
fatty-acyl-CoA binding
aldehyde dehydrogenase (NAD) activity
methylmalonate-semialdehyde dehydrogenase (acylating) activity
thiolester hydrolase activity
malonate-semialdehyde dehydrogenase (acetylating) activity
poly(A) RNA binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
dehydrogenase
