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Proteintech
ALDH8A1 Polyclonal Antibody
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产品信息
21602-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ALDH8A1 Fusion Protein Ag16214 (136-487 aa encoded by BC113862)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: CMHYTVRAP VGVAGLISPW NLPLYLLTWK IAPAMAAGNT VIAKPSELTS VTAWMLCKLL DKAGVPPGVV NIVFGTGPRV GEALVSHPEV PLISFTGSQP TAERITQLSA PHCKKLSLEL GGKNPAIIFE DANLDECIPA TVRSSFANQG EICLCTSRIF VQKSIYSEFL KRFVEATRKW KVGIPSDPLV SIGALISKAH LEKVRSYVKR ALAEGAQIWC GEGVDKLSLP ARNQAGYFML PTVITDIKDE SCCMTEEIFG PVTCVVPFDS EEEVIERANN VKYGLAATVW SSNVGRVHRV AKKLQSGLVW TNCWLIRELN LPFGGMKSSG IGREGAKDSY DFFTEIKTIT VKH (136-487 aa encoded by BC113862)
靶标信息
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; aldehyde dehydrogenase 8 family, member A1; Aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase family protein; Retinal dehydrogenase 4; retinal dehydrogenase type 4
基因别名: ALDH12; ALDH8A1; DJ352A20.2; Raldh4
UniProt ID: (Human) Q9H2A2, (Mouse) Q8BH00
Entrez Gene ID: (Human) 64577, (Mouse) 237320, (Rat) 685750
retinal dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
3-chloroallyl aldehyde dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
1-hydroxy-2-naphthaldehyde dehydrogenase activity
cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity
2-carboxybenzaldehyde dehydrogenase activity
trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity
benzaldehyde dehydrogenase activity
2-naphthaldehyde dehydrogenase activity
1-naphthaldehyde dehydrogenase activity
4-hydroxymethylsalicyaldehyde dehydrogenase activity
3-methylsalicylaldehyde dehydrogenase activity
oxoglutarate dehydrogenase [NAD(P)+] activity
oxoglutarate dehydrogenase (NAD+) activity
pyruvate dehydrogenase [NAD(P)+] activity
pyruvate dehydrogenase (NAD+) activity
citronellal dehydrogenase activity
geranial dehydrogenase activity
N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity
glyceraldehyde dehydrogenase (NADP) activity
N-acetyl-gamma-aminoadipyl-phosphate reductase activity
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
2,5-dioxovalerate dehydrogenase (NAD+) activity
medium-chain-aldehyde dehydrogenase activity
dehydrogenase
