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Invitrogen
ALKBH3 Polyclonal Antibody
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产品信息
PA5-52672
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human ALKBH3
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: WAAPVKSQAI AQPATTAKSH LHQKPGQTWK NKEHHLSDRE FVFKEPQQVV RRAPEPRVID REGVYEISLS PTGVSRVCLY PGFVDVKEAD WILEQLCQDV PWKQRTGIRE DITYQQPRLT AWYGEL
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
靶标信息
Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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