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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.3-1 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Rat |
宿主/亚型 |
Goat / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide sequence (ERNKKKQLPYYYLSPD) corresponding to the C-terminus amino acids of ALOX5 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
TBS, pH 7.3, with 0.5% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_10979140 |
This antibody is predicted to react with canine and mouse based on sequence homology.
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5 - Lipoxygenase; 5-lipoxygenase; 5-LO; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; leukotriene A4 synthase; LOX-5; lox5; Polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
基因别名: 5-LO; 5-LOX; 5LPG; ALOX5; LOG5; LOX5A
UniProt ID: (Human) P09917, (Rat) P12527
Entrez Gene ID: (Human) 240, (Rat) 25290
分子生物学功能:
oxygenase
reverse transcriptase
