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Positive control: LNCaP cell lysate, A375 cell lysate, Mouse kidney tissue lysate, Rat kidney tissue lysate, human prostate cancer tissue, human renal cell carcinoma tissue, human kidney tissue, mouse kidney tissue.
Subcellular location: Peroxisome, Mitochondrion.
P504S/AMACR/a-Methylacyl-CoA Racemase is an essential enzyme in the b-oxidation of branched-chain fatty acids. High expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded tissue. The expression of P504S is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2-arylpropionyl-CoA epimerase; 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; alpha-methylacyl-Coenzyme A racemase; amcr; OTTHUMP00000219978; OTTHUMP00000219979
基因别名: AMACR; AMACRD; CBAS4; Da1-8; Macr1; Marc1; RACE; RM
UniProt ID: (Human) Q9UHK6, (Mouse) O09174
Entrez Gene ID: (Human) 23600, (Rat) 25284, (Mouse) 17117