Invitrogen

AMER2 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他3个AMER2抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (3)
高级验证 (1)

AMER2 Antibody in Immunohistochemistry (IHC)

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AMER2 Antibody (PA5-58794) in IHC

Immunohistochemical staining of AMER2 in human cerebral cortex and pancreas tissues using AMER2 Polyclonal Antibody (Product # PA5-58794). Corresponding AMER2 RNA-seq data are presented for the same tissues.

Product Image Gallery

AMER2 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of AMER2 demonstrates antibody specificity. Immunohistochemical analysis of AMER2 using anti-AMER2 Polyclonal Antibody (Product # PA5-58794), shows significant staining of AMER2 in human cerebral cortex and shows minimal or weak staining in human pancreas tissues. The relative expression levels of AMER2 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-58794

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化 (IHC)

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human AMER2. Recombinant protein control fragment (Product #RP-97993).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.15 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2637902

产品详细信息

Immunogen sequence: VDDTYLQEFW DMLSQTEEQG PEPQEGAAKV AAALETKVVP ETPKDTRCVE AAKDASSVKR RRLNRIPIEP HPKEEPKHPE KEQQE

Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

靶标信息

Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.

仅用于科研。不用于诊断过程。未经明确授权不得转售。