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Proteintech
AMFR Polyclonal Antibody
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产品信息
16675-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AMFR Fusion Protein Ag10178 (301-643 aa encoded by BC069197)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LFHEVQRRI RRHKNYLRVV GNMEARFAVA TPEELAVNND DCAICWDSMQ AARKLPCGHL FHNSCLRSWL EQDTSCPTCR MSLNIADNNR VREEHQGENL DENLVPVAAA EGRPRLNQHN HFFHFDGSRI ASWLPSFSVE VMHTTNILGI TQASNSQLNA MAHQIQEMFP QVPYHLVLQD LQLTRSVEIT TDNILEGRIQ VPFPTQRSDS IRPALNSPVE RPSSDQEEGE TSAQTERVPL DLSPRLEETL DFGEVEVEPS EVEDFEARGS RFSKSADERQ RMLVQRKDEL LQQARKRFLN KSSEDDAASE SFLPSEGASS DPVTLRRRML AAAAERRLQK QQTS (301-643 aa encoded by B C069197)
靶标信息
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AMF receptor; Autocrine motility factor receptor; autocrine motility factor receptor, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase AMFR; gp78; RING finger protein 45; RING-type E3 ubiquitin transferase AMFR
基因别名: AMFR; GP78; RNF45
UniProt ID: (Human) Q9UKV5, (Mouse) Q9R049
Entrez Gene ID: (Human) 267, (Rat) 361367, (Mouse) 23802
ubiquitin-protein transferase activity
receptor activity
protein binding
zinc ion binding
ligase activity
protein binding, bridging
ubiquitin-ubiquitin ligase activity
chaperone binding
ubiquitin protein ligase activity
ubiquitin protein ligase activity involved in ERAD pathway
BAT3 complex binding
ubiquitin-specific protease binding
molecular_function
nucleotide binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein modifying enzyme
protein polyubiquitination
ubiquitin-dependent protein catabolic process
movement of cell or subcellular component
signal transduction
aging
learning or memory
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
positive regulation of protein binding
ERAD pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
protein oligomerization
protein autoubiquitination
protein K48-linked ubiquitination
cellular process
