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Invitrogen
AMIGO1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-38045
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
19 amino acid peptide near the carboxy terminus of human AMIGO1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A recommended positive control is HeLa cell lysate.
AMIGO1 antibody is not expected to cross-react with AMIGO2 or AMIGO3.
靶标信息
Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alivin 2; alivin-2; AMIGO 1; AMIGO-1; amphoretin-induced gene and ORF; amphoterin induced gene and ORF (Amigo); amphoterin-induced gene and ORF; MGC25558; OTTHUMP00000013379; RP23 89M15.6; transmembrane protein AMIGO; unnamed protein product
基因别名: ALI2; AMIGO; AMIGO-1
UniProt ID: (Human) Q86WK6, (Rat) Q80ZD7, (Mouse) Q80ZD8
Entrez Gene ID: (Human) 57463, (Rat) 295365, (Mouse) 229715
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
axonogenesis
axonal fasciculation
brain development
positive regulation of neuron projection development
myelination
positive regulation of axonogenesis
positive regulation of cellular component organization
positive regulation of nervous system development
positive regulation of synapse assembly
neuron projection fasciculation
positive regulation of potassium ion transmembrane transport
cellular response to L-glutamate
cell adhesion
positive regulation of voltage-gated potassium channel activity
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