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Proteintech
AMIGO3 Polyclonal Antibody
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产品信息
21278-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AMIGO3 Fusion Protein Ag15790 (221-504 aa encoded by BC110418)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LPCDCRLYH LLQRWHQRGL SAVRDFAREY VCLAFKVPAS RVRFFQHSRV FENCSSAPAL GLERPEEHLY ALVGRSLRLY CNTSVPAMRI AWVSPQQELL RAPGSRDGSI AVLADGSLAI GNVQEQHAGL FVCLATGPRL HHNQTHEYNV SVHFPRPEPE AFNTGFTTLL GCAVGLVLVL LYLFAPPCRC CRRACRCRRW PQTPSPLQEL SAQSSVLSTT PPDAPSRKAS VHKHVVFLEP GRRGLNGRVQ LAVAEEFDLY NPGGLQLKAG SESASSIGSE GPMTT (221-504 aa encoded by BC110418)
靶标信息
Amphoterin induced gene and ORF 3 (AMIGO3) is a gene located on chromosome 3p21.31, encoding a member of the AMIGO family of proteins involved in cell adhesion, axon guidance, and neuronal signaling. AMIGO3 is primarily expressed in the central nervous system, playing a crucial role in neural development and the maintenance of neural circuits. Functionally, AMIGO3 contributes to neuronal growth and synapse formation, impacting processes such as neural plasticity and signal transduction. The protein's activity facilitates interactions with other neuronal surface proteins, influencing axon pathfinding and connectivity. Aberrant expression or mutations in AMIGO3 have been linked to neurological disorders and neurodegenerative diseases, suggesting its significance in neural health and pathology. Research into AMIGO3 continues to explore its potential therapeutic applications in promoting neural repair and modulating synaptic functions, offering insights into strategies for addressing nervous system disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion molecule with Ig-like domain 3; alivin 3; Alivin-3; AMIGO-3; AMIGO3; amigo3 {ECO:0000312|EMBL:AAO48952.1, ECO:0000312|RGD:631413}; amphoterin induced gene and ORF 3; amphoterin-induced gene and ORF 3; Amphoterin-induced protein 3; MGC120552; transmembrane protein AMIGO3
基因别名: ALI3; AMIGO-3; AMIGO3; E430002N15Rik; KIAA1851; mKIAA1851; UNQ6084/PRO20089
UniProt ID: (Human) Q86WK7, (Rat) Q80ZD5, (Mouse) Q8C2S7
Entrez Gene ID: (Human) 386724, (Rat) 316003, (Mouse) 320844
