Search
Rockland
AML-ETO Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
AML-ETO Antibody (600-401-X43) in WB
Western Blot analysis using Anti-AML-ETO. Figure A: Schematic representation of the construction of GST-fusion proteins containing different parts of AML-ETO were constructed and run on a 15% polyacrylamide gel. Figure B: Western Blot was performed on seven GST-fusion proteins containing different fragments of AML-ETO (1-7) with Anti-AML-ETO, diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (in kDa) is shown on the left; the location of the protein of interest is indicated on the right. The antibody raised... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
600-401-X43
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-AML-ETO Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides from the human AML-ETO fusion protein. The antibody recognizes the ETO (RUNX1T1) part of the fusion protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 µg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.05% ProClin 300, 0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: acute myelogenous leukemia 1 translocation 1 protein; CBFA2T1 identified gene homolog; Cyclin-D-related protein; Eight twenty one protein; MGC2796; MTG8b; Protein CBFA2T1; Protein ETO; Protein MTG8; Zinc finger MYND domain-containing protein 2
基因别名: AML1T1; CBFA2T1; Cbfa2t1h; CDR; ETO; MTG8; RUNX1T1; ZMYND2
UniProt ID: (Mouse) Q61909
Entrez Gene ID: (Mouse) 12395
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
