Proteintech

ANAPC7 Polyclonal Antibody

Name: ANAPC7 Polyclonal Antibody
Brand: Proteintech
SKU: 21761-1-AP

查看其他8个APC7抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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ANAPC7 Antibody (21761-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 21845-1-AP (PYROXD2 antibody) at dilution of 1:2,000 incubated at room temperature for 1.5 hours.

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产品信息

21761-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:16,000

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ANAPC7 fusion protein Ag16339

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

450 µg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Sequence of this protein is as follows: QMLDPYLIKG MDVYGYLLAR EGRLEDVENL GCRLFNISDQ HAEPWVVSGC HSFYSKRYSR ALYLGAKAIQ LNSNSVQALL LKGAALRNMG RVQEAIIHFR EAIRLAPCRL DCYEGLIECY LASNSIREAM VIANNVYKTL GANAQTLTLL ATVCLEDPVT QEKAKTLLDK ALTQRPDYIK AVVKKAELLS REQKYEDGIA LLRNALANQS DCVLHRILGD FLVAVNEYQE AMDQYSIALS LDPNDQKSLE GMQKMEKEES PTDATQEEDV DDMEGSGEEG DLEGSDSEAA QWADQEQWFG MQ

靶标信息

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.

仅用于科研。不用于诊断过程。未经明确授权不得转售。