Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA1-1053
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues C(80) Q G P K G K D A P F K D S E(94) of mouse FIAF.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2057436
产品详细信息
PA1-1053 detects fasting-induced adipose factor (FIAF) from rat and mouse adipose tissue.
PA1-1053 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~50 kDa protein representing FIAF from rat adipose tissue extracts.
The PA1-1053 immunogen is a synthetic peptide corresponding to residues C(80) Q G P K G K D A P F K D S E(94) of mouse FIAF.
PA1-1053 can be used with blocking peptide PEP-178.
靶标信息
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 425O18-1; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; Fasting-i; Fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; Secreted protein Bk89
基因别名: Angptl4; Arp4; Bk89; Farp; Fiaf; Hfarp; Ng27; Pgar; Pgarg; Pp1158
UniProt ID: (Mouse) Q9Z1P8, (Rat) Q6TMA8
Entrez Gene ID: (Mouse) 57875, (Rat) 362850
angiogenesis
cellular response to starvation
negative regulation of apoptotic process
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
protein homooligomerization
triglyceride homeostasis
negative regulation of endothelial cell apoptotic process
response to hypoxia
regulation of lipid metabolic process
cell differentiation
negative regulation of catalytic activity
protein oligomerization
