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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.2-1.0 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
synthetic peptide directed towards the N terminal region of human ANKMY2 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5-1.0 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS with 2% sucrose |
内含物 |
0.09% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2689221 |
This target displays homology in the following species: Cow: 100%; Dog: 92%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Yeast: 90%
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ankyrin repeat and MYND domain-containing protein 2
基因别名: ANKMY2; ZMYND20
UniProt ID: (Human) Q8IV38
Entrez Gene ID: (Human) 57037
