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Invitrogen
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Immunogen sequence: KRCQYEPDYR DNCGVTALMD AIQCGHIDVA RLLLDEHGAC LSAEDSLGAQ ALHRAAVTGQ DEAIRFLVSE LGVDVDVRAT STHLTA
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ankyrin repeat domain-containing protein 16
基因别名: ANKRD16
UniProt ID: (Human) A6NEF0
Entrez Gene ID: (Human) 54522