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Invitrogen
ANP Polyclonal Antibody
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产品信息
PA3-228
产品规格
种属反应
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic cyclized peptide corresponding to ANP
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
whole serum
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA3-228 detects Atrial Natriuretic Peptide in rat samples. PA3-228 is expected to react with human samples due to sequence homology.
PA3-228 has successfully been used in WB and mmunocytochemical procedures.
The PA3-228 immunogen is a synthetic cyclized peptide corresponding to ANP.
靶标信息
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: atrial natriuretic factor; Atrial natriuretic factor prohormone; atrial natriuretic peptide; Atrial natriuretic peptide prohormone; Atriopeptigen; Cardiodilatin; CDD; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor type A; Natriuretic peptides A; preproANF; preproANP; preproCDD-ANF; prepronatriodilatin; Pronatriodilatin; urodilatin
基因别名: ANF; ANP; Nppa; Pnd; RATANF
UniProt ID: (Rat) P01161
Entrez Gene ID: (Rat) 24602
response to hypoxia
negative regulation of systemic arterial blood pressure
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
neuropeptide signaling pathway
heart development
female pregnancy
regulation of blood pressure
positive regulation of heart rate
cardiac muscle hypertrophy in response to stress
negative regulation of cell growth
response to insulin
regulation of body fluid levels
regulation of blood vessel size
multicellular organismal water homeostasis
regulation of atrial cardiac muscle cell membrane repolarization
positive regulation of cardiac muscle contraction
cellular response to mechanical stimulus
regulation of high voltage-gated calcium channel activity
positive regulation of delayed rectifier potassium channel activity
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
positive regulation of potassium ion export across plasma membrane
negative regulation of collecting lymphatic vessel constriction
