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This antibody detects endogenous protein at a molecular weight of 27 kDa.
Purity is >95% by SDS-PAGE.
ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acidic (leucine-rich) nuclear phosphoprotein 32 family, member C; Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; pp32 related 1; Tumorigenic protein pp32r1
基因别名: ANP32C; Anp32c-ps; Anp32cl; EG448829; PP32R1
UniProt ID: (Human) O43423
Entrez Gene ID: (Human) 23520, (Mouse) 448829
分子生物学功能:
chromatin/chromatin-binding, or -regulatory protein
