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Invitrogen
AP2 alpha Polyclonal Antibody
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产品信息
PA1-25327
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, conjugated to KLH, corresponding to residues S(420) H T D N N A K S S D K E E K H R K(437) of human AP2 alpha.
偶联物
形式
Liquid
浓度
0.9 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Recommended positive controls: HeLa nuclear extract.
PA1-25327 is expected to cross react with mouse (94% conserved), rat (94% conserved), chicken (88% conserved), and ovine (94% conserved) due to sequence homology.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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