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Invitrogen
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MA1-91376 detects AP2 beta from human samples.
MA1-91376 has been successfully used in Western blot applications.
The MA1-91376 immunogen is: Truncated AP-2 beta-protein prepared from bacteria.
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
仅用于科研。不用于诊断过程。未经明确授权不得转售。