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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adaptor-related protein complex 3 subunit mu-1; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; ap3; Mu-adaptin 3A; Mu3A-adaptin
基因别名: AP3M1
Entrez Gene ID: (Human) 26985